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High Risk

Questions about PEP and test results

Hello, here is my case: I had sex with another man I met online. Before meeting we talked about our safe sex habits and we both said that we never practice unsafe sex (for what it’s worth this was very clear in his profile by the way). He brought condoms and lube the first time we met which is always a great sign. We met a second time a month or two later. Again before meeting he asked if I had condoms at home (again great). This second time unfortunately the condom broke towards the end (I check often to make sure it is fine), and I only noted when we were finished. I had an exposure of about 2/3 minutes at the most. I’m top only but uncircumcised.
I totally panicked even though I don’t honestly have any reason to think that my partner engages in risky behaviors as he seemed concerned about bringing and using condoms (but he is bottom only and accidents with condoms happen). He was also upset but he did not panic as much as I did which made me even scarier. We talked about the incident and he said that he got tested about 2 months before and that everything was fine and that he hadn’t been with anyone since (but who knows right?).
After he left I decided to go to A&E and get PEP. The doctor prescribed Truvada+Ralgetravir (all STD baseline tests were negative) and I took the first dose about 8 hours after the exposure. I took all doses exactly as prescribed – or so I thought - for the full 28 days. As it happens I had to visit relatives so I took medication for the 10 days I was with them and hid it in my bag (this was between days 6 and 16 of PEP). The morning pills were easy to take (2 pills) because nobody was home but the evening pill was harder so I sometimes kept it in my pocket and then went to the bathroom when it was time to take it. As it happens a few weeks later (after completing the course of PEP) when I returned to my family’s house I found a Ralgetravir pill in one of my jeans and I panicked. I could swear I didn’t miss any dose but now I’m not sure whether they gave me one extra pill of if I missed one. Anyway, I’m absolutely sure I took every other pill as prescribed (I’ve been really stressed and not sleeping well so I may have missed that one).
2 weeks after completing PEP (and 6 weeks after the exposure) I went back to the clinic and got an insti hiv1/hiv2 rapid test which was negative. I was quite happy with the outcome as I read that the test is very sensitive and detects both Igg and Igm antibodies and is now therefore considered a 3rd generation test which is useful in detecting early seroconversion. The New York State Department of Health AIDS Institute has a test comparison sheet where it says that the window period for the INSTI is 4-6 weeks. So here are my questions
1) would that 1 Ralgetravir pill I may have eventually missed lower the efficacy of PEP? I hear that some people take truvada only as PEP and I didn’t miss any of those. I also read that experts aim for a 95% adherence rate but I’m not sure whether that applies to PEP.
2) What can I take from this 6 week negative result? Have you ever seen a case where someone who took PEP and got this result would later seroconvert?
3) I’ve read a lot about delayed seroconversion after PEP. The revised CDC guidelines ask for testing up to 3 months post-exposure (not post-pep) and the revised UK guidelines ask for tests 4-6 weeks post PEP (which is basically the same). The experts at thebody.com say that delayed seroconversion is a myth. I have searched the academic journals and found reports of older cases (1990s) where the timing of testing was not always clear and a report of a monkey in an animal study. I also found an interesting report reviewing seroconversion cases among health care workers. Though not all cases were offered PEP there didn’t seem to be a noticeable difference in the time of confirmation of seroconversion between PEP and non-PEP takers. What is your view on this?
I’m still waiting to go back for my 12 week test. In the meantime, I managed to talk to my partner through the dating site to tell him that I got tested. He replied saying that the got tested too and was fine. I know I should probably be happy with this but I’m totally paranoid and that is only a modest comfort for me.

Many thanks for your help!

Late seroconversion due to hepatitis B?

Hello, in drunk state I topped a guy that I know unprotected ( Insertive anal sex).
About a month after, my eyes turned yellow I got tested and came back positive for Hepatitis B. I freaked out and asked that guy to get tested he came back POSITIVE for BOTH HIV and Hepatitis B ( I know he injects drugs so I shouldn't be surprised). Now it is 15 weeks after exposure, I got tested for HIV and It came back negative? How conclusive is that? I read that Hepatitis can delay seroconversion, is this true? Also, if Hepatitis B and HIV are passed the same way, is it possible that I only contracted one of them from a guy that is coinfected with both? Why would that happen? Now I have to wait till six months mark and get tested again for Hepatitis B to make sure that I will not be chronic carrier, should I also get tested for HIV at the same time to be sure?
Thank you

Worried Sick

Gentleman,

40 days ago I had vaginal sex with an escort and the condom broke. I have been a complete basket case worrying about this. I took an oraquick test today which came back negative. 21 days after this happened I ate a seafood dinner and got sick with diarrhea and ate nothing for a day and a half. I have been a complete wreck. Six days after the incident, I went to planned parenthood and was checked for STD's which were negative and they said it was too soon to check for HIV. Any thoughts, I am driving myself crazy. Today I woke with a slight sore throat and I almost can't function.

Possible exposure

Hi,
I had sex with a call girls. And at some point the condom broke and I ejaculated inside her. I am freaking out. I know am in possible exposure it's been 5 days. How long should I wait to get tested.

WHAT IS RIGHT DIAGNOSIS AFTER SOME BODY IS EXPOSED TO HIV/AIDS THROUGH UNPROTECTED SEX UNPROTECTED SEX

Dear

Had unprotected sex with a lady on 9th march 2016 (4-5 rounds on three occasions) letter when we tested the lady was positive with Determine. am worried, my first test with rapid test showed negative, in 21 days after last exposurer, Did PCR they said NO HIV DNA seen. in other laboratory after 56 days another laboratory results said my immune Virus-DNA quantitative less than 12iu/ml and this lies below cutoff point, but weak signal detected plus DNA, am infectious, when to another viral research centre at 58 days, they did rapid test (determine, stapak, unigol) all negative, cambo negative and try viral load, no HIV virus copies detected and at 76 days after last exposuser, determine still negative, which test should l believed in, am worried, becouse had even pharyngitis now but am being allergies to cold wherther and sit in a room with AC as an office.

Condom broke

hi

I had my condom break while I was busy, soon as I heard the pop sound
I stopped and changed it, should i be worried since I don't know the
results of the person I was with, thanx

I got raped when I was a child and now suspect to have HIV

I am a guy and I got raped when I was at the age of seven. And then now I am 24, only the symptoms of hiv appear. Is this case possible ? It is already more than 15 years.

willbroad kaovela

i had unprotected sex with affected girl 4 month but on 5week after infection are measured HIV Elisa but result was negative but now i suffered from some wound in my lips and my penis now giving some sort of pus.

WINDOW PERIOD FOR ALERE HIV1/2 DETERMINE KIT

i had unprotected sex in February and i have been using alere hiv1/2 determine kit and today makes it 3 months and am negative. Does it mean am confirmed negative

Availability of HIV Duo test in Ontario or eleswhere

Good Day,
I’m a resident in Cambridge Ontario, and I had unprotected vaginal sex with a high risk partner approx. 4 weeks ago. I recently had a rapid test, which was negative, and I understand this test is unreliable prior to 12 week from exposure.

My question is, where can I go for the Duo test within my area or elsewhere even in the US? The stress of not knowing is wearing me down, and I’m prepared do whatever necessary to get tested with the Duo test. It would help to have some reassurance now, but I will also do a follow up test at 3 months.

Thank you your assistance is very much appreciated.

Cheers,
Denis

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