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Pooled RNA/Early Test

question about testing

Hi there I am just wondering that when getting a test done hiv if you have to tell the doctor the type of sex you had. For example is there a different test for unprotected anal vs unprotected vaginal sex or is just the standard blood test for all sexual acts. Do I have to tell the doctor what I engaged in or can I just be confident in requesting a test and not worry about giving full details to the doctor.

please assess my risk, should i relax now?

hi,

i am extremely worried and depressed for the past 2 months over a mistake i made. i had a high risk exposure with a CSW. i was under influence of heavy alcohol and had a brief 30 second unprotected vaginal sex with a CSW. she sucked my nipples and later i wore a condom and I had protected vaginal and oral sex. I just went to sleep as i was so drunk and when I woke up the CSW was gone with my purse and belongings. Later when i tried to call she never picked up. I recall everything and dats y i remember penetrating her for about 15-30 seconds without condom. I also remember she gave me unprotected handjob.This incident happened on april 7. I got a mouth ulcer on may 2 which subsided on may 5 after I used orasore. then again last week i had 2 small mouth ulcers which disappeared in a day after I used orasore and also very mild diarrhea which lasted 3 days. no fever nothing. as i got very scared about hiv i decided to test. I did not know anything about PEP dats y i could not start in within 3 days of exposure.please refer below for my testing details:-

please refer to my test results below:-
risk date- april 7,2016

hiv-1 rna QUANTITATIVE pcr on april 18- negative, target not detected (10 days after exposure)

hiv 1/2 & p24 antigen combo test(CMIA) on may 6- index value- 0.07 negative(28 days after exposure)

hiv-2 pcr detection on may 14- negative,target not detected(37 days after exposure)

hiv 1/2 & p24 antigen combo test(CMIA) on may 21- index value- 0.11 target not detected(44 days after exposure)

hiv-1 rna QUALITATIVE PCR on may 23- negative, target not detected(46 days after exposure)

hiv 1/2 & p24 antigen combo test(CMIA) on june 2- index value- 0.07 target not detected(56 days after exposure)

the hiv specialist doctor I have been consulting online has said that my results r conclusive and i dont need to worry now and no need for further testing. should i test on june 30 which is 84 days or my results r conclusive now?

Anonymous

I had a reactive result to my HIV 1+2 Ab + HIV p24 AA test. Then they re-ran the test (protocol) and the HIV 1 RNA (PCR/NAAT) test found "No HIV 1 RNA detected" and the interpretation was that it was not consistent with HIV infection but a follow up EDTA is required to confirm.
I am now waiting for the results of the EDTA and my anxiety is through the roof!!
What are the chances that the initial test was a false positive? Is it more likely that the first test was a false positive or that the second test was a false negative?

Anxiety

I've been through two incidents prior to this, the first (unprotected sex) and second (dabbing) which had caused me to live in anxiety for a long time. However I was tested negative for both situations (multiple tests over three months period after exposure) and stopped having sex.

However recently I just got into another incident, where the guy did not have a condom and rubbed his penis on me for minute? I immediately told him to stop after feeling a slight jab on my anus. I don't think it penetrated, there was no lube and I did not feel any pain at all. I was also able to stop the movement with my buttcheeks. I fear it penetrated, since I did not have sex for a long time and rarely do in the first place I would not know. Also there was no fluid, as the whole situation was very abrupt.

Again now im suffering from anxiety and counting the days until i can get tested in six weeks, meanwhile unable to do anything because of my agonizing mind. It may be because I had such bad prior experiences, that im so used to worrying. I was hoping that you could briefly asses my risk? also for future reference, what signals/feelings constitutes that something has penetrated into me?

HIV Infection

Hi There,

I have been to a lady a month back. I am little worried of myself now. What I did is I rubbed my penis on her vagina and while rubbing I inserted the tip of my penis and suddenly i realized and took off. Wore condom that had sex. But m still worried if I can get HIV transmitted. Since she was an unknown lady i am not sure of her. status. Please advice me. Thanks

can pcr detect hiv 2

hello.
the exposure was in India so HIV 2 is a concern. DUO test was a negative after 3 months but there are reports online of carriers of the HIV 2 virus in India who somehow did not seroconvert (would really appreciate if someone go through the article). My question is, can PCR RNA detect both HIV 1 and 2 virus and all subtypes if the DUO missed it? Is this the right test for this situation for patients who do not seroconvert? thank you.

Potential HIV exposure

Dears,
Well, i recently had unprotected sex with a (trans person) it was insensitive action by me, noting that it was 10 days ago.
he or she is working for paid sex.
also it was one time only even before that time i didn't expose my self to risky sex.
I took RNA test after 2 days but i think from what i read it wont be reliable.
I am planning to have another RNA test after 10+ mark.
Will that be enough?
Should i take another test after 45 days or 3 months?.
Note: i am very stressed over this and i don't have any symptoms of HIV (flue, Rash ....)
I had my dual anti body and RNA test at 10 days mark, the result is negative, am i still at high risk?
Thank you for your support.

Protected sex with a female CSW, but with a *potential* tear in the condom

Hello.
Two nights ago I had sex with a female CSW and we engaged in unprotected oral sex(which I understand is negligible risk) and two seperate occasions of protected vaginal sex.

During the second episode of vaginal sex, the heater in her room got me fatigued so I took a few minutes to cool down. When we started again I felt a cool sensation on the tip of my penis, she usually applies lube to her vagina, the condom, or both-- which she did as we started to have sex again. However it felt much cooler than I would expect to feel from outside of latex so I pulled out, near immediately.

The condom had no visible signs of breakage, in fact the reservoir tip was elongated (I always pinch the air out of the tip when I roll it down) We decided that since it had been a while since I put the condom on we might as well put a new one on, as to not wear this one out.

If it makes any difference I'm uncircumcised (very rare in the US, especially rare in Los Angeles where I live), but my foreskin retracts completely, and I always roll the condom on after pulling the skin all the way back. For all intents and purposes, I apply condoms the proper way.

I slipped the old one off-- while I didn't notice anything torn or unusual when pulling it off-- I also didn't check carefully and it was dark inside her bedroom.

Now in the sober light of day I'm terrified because I have never had a condom break on me, so I have no reference point for how it feels what so ever.

Other than the loss of my virginity nearly 10 years ago, I have always worn condoms with every sex partner I've had, whether it be a girlfriend, a one night stand, or a sex worker.

And I know that just because she is a sex worker doesn't mean that she has anything, but never the less I'm worried, as I know that she does have a lot of partners.

I'm upset with myself that I did not run the condom under the sink to check and make sure it passed the water test-- I figured I was being safe enough, switching during the uncertainty.

I can't stress the fact that I really don't know if there was a tear or not, if so it was not an obvious condom 'pop' like my friends have told me about.

I'm so worried I'm nauseous, I can't leave my apartment or think about anything else. I just keep thinking what a stupid way to contract such a horrible disease, and while I don't see sex workers habitually, it is something I do a couple times a year when I'm lonely, and actually I only go to the same girl. I'm don't think I can handle the risks involved anymore.

I guess I'm wondering how much my risk is increased (been too scared to google it-- that always makes anxiety worse) and if it would be appropriate to take PEP, or if that's over kill. I would also like to know how soon I can get an RNA test, I know that the window is 2 weeks, but I've been wondering if that's shrunk at all over the years? Like how 6 weeks is a pretty good indicator for the antibody test, would a week be a decent indicator for an RNA/NAAT test?

Again, I don't know if the condom broke, I just don't know. I wish I could tell you. All I know is something felt different, but not in that "oh god it just got better' obvious condom break way. At least from what I've been told.

Thank you for your help, what you do is incredibly commendable and I'm sorry for any excess information, I'm just quite scared.

2 time false-positive CMIA?

Hello,

hope can get help - lets see my story:
My gf was tested, and here results were two times CMIA reactive - this arround 5, and 2 weeks ago. Booth time she were tested with other tests too, here the result:
- ECLIA, negative
- immunochromography, negative

She did NAT, and viral load test (PCR) too - there the result were also negative. Doctor says, can happen that some people many times false-positive CMIA, and we should not worry.

Me still worried - had many tests, all negative, the last was HIV Duo Quick, and HIV Combo HIV-1-2 AG/ AB, this after 4 weeks whe I had last time sex with her.

Can I relax now, or still should be worried? I had few symptoms, hm, like fever, diarrhea, swollen lymph nodes. Hm, more worried I'm because i never read information about 2 times CMIA false-reactive.

Thanks.

HIV Risk

Hi all,

I would be grateful for any advice. Last week I had unprotected sex with a woman I met for the first time. I had been drinking and in the heat of the moment I failed to take precautions. The intercourse lasted no longer than 3 minutes, in truth I would be surprised if it lasted longer than one minute, I ejaculated inside her (not worried about pregnancy as she assured me she is on the pill), later (minutes after we had finished) she got her period.

In the past outside of relationships I’ve always been careful so I’ve never worried about HIV or passing it on to someone. It would be entirely hypocritical of me to be judgemental, but as she never asked me to take precautions I presume that she has not asked other partners to do the same. With that in mind I’m very worried that she could have picked up something that I may have caught. Short of her behaviour with me I’ve no reason to think that she may have anything. This week I’ve been so overwhelmed with worry that I felt I had to ask her if she had anything and her recent sexual history. She said that the last two people before me she had unsafe sex with were her partner of 5 years (who she split up with in December) and before that the father of her son. She said that while she has slept with other men since, she has always used protection until me as while she took a lot of risks before having her child (in the UK women are tested for HIV when they are pregnant) he was too important to her to do so again and that she has no STDs.

Additionally, I’m not sure if this is relevant but she also told me she has suffered from Endometriosis since she was 16 (she is now 31) and recently has had a full insertive pelvic exam and smear tests relating to this. I know only the HIV test actually checks for the virus but I presume other STDs are visible during the exam and come up in some of the tests. Could these tests give doctors an inclination if she was suffering from HIV? I mean if for instance her white blood cell count was low etc could that be cause for further query on the doctors part.

I have had friends who have had similar mistakes in the past and picked up things like Herpes and Chlamydia, when I googled for them I found HIV. I have read that it is unlikely for the penetrative partner in vaginal sex to pick up the virus but it’s a chance I’ll never take again if I’m lucky enough to avoid HIV this time. It may sound silly but at the moment I’m really unconcerned about having picked up other STDs from her – HIV seems to put them all into perspective. In terms of symptoms I’ve been so anxious that I’m interpreting everything in a really scary way. I have had a bruise from the gym, a red mark from leaning on my arm and a spot which I have attributed to HIV only for them to disappear within minutes or hours. Since the second day it happened throat has been mildly uncomfortable – particularly when I think about it, and I’m worried it could be a sign of the virus but I am hoping it is stress or even a common cold. I have a spot on the skin between my testicles and penile shaft, I called another STD nurse when I noticed and she told me this was not a symptom of HIV. My temperature does not appear to be fluctuating, although I know many people with HIV do not have symptoms.

I’m from Scotland in the UK and the women I had sex with was not African/Eastern European or a sex worker (not trying to offend anyone, those are just higher risk categories in the UK, along with men who have sex with men from what I have read). Nor is she an intra venus drug user. A sexual health nurse I spoke to on the phone said it was very unlikely that the woman would have HIV and even more unlikely that I’d pick it up…A volunteer on the phones of the Terence Higgins Trust (UK based HIV charity) had already said a similar thing to me but I just thought it would be worthwhile asking here. I

I wondered if more learned people than myself could answer a few questions. Firstly – does the length of contact matter? I understand that HIV can be passed the first time you come into contact with someone or may not be passed after 100 times, but I wasn’t sure if the length of time was a factor. Also, if she was menstruating while we had intercourse would that increase the likelihood of me picking up something? Finally I wondered how long I should wait before I get a test. I’ve heard of 11 day tests but when I spoke to the nurse/THT they suggested it was more common to wait a month for the first (and generally conclusive) test. I've also read that the 11 day RNA test has a high rate of false positives and I wondered if that was why it was generally only used for those who have almost definitely come into contact with HIV.

This has really worried me and I feel like it is the biggest mistake of my life. I feel like I have anxiety issues for worrying this much but I feel like I need to know as much as I can. I've managed to persuade the woman I had sex with to come with me for a Rapid HIV test next week, which if she's telling the truth about no unprotected sex, should reveal if I'm in danger (obviously I'll still go for further tests to be sure).

Thank you very much for taking the time to read this, I’m very grateful for any advice and answers anyone can offer.

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