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I have a congenital condition of very low IgM counts

does the condition mentioned in the title constitute a risk of false hiv negative testing using a 4th gen. duo test at day 42 after possible exposure ?

Not enough antibodies at 3 months?

I had sex with a RLD Amsterdam prostitute 3 months ago. I used a condom, for both oral and vaginal sex. I had no worries since I protected myself and I'm aware of the precautions the Netherlands workers use (condoms for everything including oral).

3 weeks ago however, I had a small cut injury (no bigger than 10cm and I had no bleeding), I quickly tried to disinfect it but left it wet with the disinfectant liquid right after I received the cut (day and night for two days), I didn't try to cover the wound or anything (I'm starting to believe that leaving the wound wet and moist while still doing normal day activities like public transportation is what got me infected). The cut was from a barrel that had a metal safety belt thingy ( I cut myself with the metal), however the contents of the barrel were toxic chemical residues from a sink drain in a laboratory. 3 days after the cut it got infected very bad with a bacteria, it extended to at least 40 cm more from the origin of the cut, I began to swell and had blisters filled with pus all around it, the first doctor diagnosed that I should take Ciprofloxacin, the second doctor said this was a mistake and I had to take Dicloxacillin instead, fast forward 3 weeks later and the wound has almost completely healed with new skin.

Around the same time of my cut, I noticed two pearly bumps around my pubic hair, thinking it was pimples I squeezed them and white liquid came out with a little blood, afterwards I noticed two more bigger sized bumps, the same doctor that misdiagnosed me gave me a fungus cream medicine for it, saying it was probably fungus and that it should go away quickly without even looking at the bumps, he just asked me what they looked like and made a prescription based on that.

Fast forward 2 weeks, after noticing no improvement with this cream and actually getting worse and I was diagnosed with Mollscum contagious by a dermatologist, he told me this was an awful prescription that my previous doctor game me, and that it made a simple problem extend much bigger, since the virus has spread around my pubic hair area with more bumps, he made me realize it was because I kept rubbing the molluscum pimples around other areas of my body). I had cryotheraphy since then and have controlled the infection somewhat (I'm still not entirely molluscum free).

Here's where I began to worry, both of these disseases suggest after reading on the internet, that while it may happen on normal people, it may happen more often with people who have a weakened immune system by HIV. So of course, I panicked, feeded my brain with negative thoughts and haven't been able to shake off this whole thing by constantly reading on the internet day after day to the point of depression.

I did the most logical thing, which was to get a test. I tested at around 84 days after that sex encounter exposure and the test result came back negative, I've read online that this should be considered a conclusive result since around 99% of people would've presented enough antibodies to be picked up by then.

I wasn't convinced enough so I did a second test at 15 weeks (in a different clinic as well) and came back negative again.

Should I leave this matter to rest now? I had no worries about my sex encounter until these two things happened, it just worries me that these things happened around the same timeframe and worsened so fast. Should I chalk it up to bad first doctor medications?

How safe am I that this is a conclusive result at 15 weeks?

Thank you for reading.

please assess my risk, should i relax now?

i had an exposure with a CSW on april 7. she sucked my nipples and gave me a blowjob. It was protected oral sex and I was wearing condom throughout. I did not have any vaginal or anal sex with the girl. She gave me an unprotected handjob. Later She lied naked with me for half an hour and later I just chatted with her about her life, why she became a sex worker and if anyone in her family knew about what she did. I felt really bad after her hearing her story and felt I was exploiting someone and just asked her to go without having even any protected penetrative sex.

I dont know her HIV status but she insisted on using condoms for oral sex even though I was willing to go for oral without condom,saying she needed to protect herself. She also refused anal sex,saying she never has it and only has vaginal sex with a condom and told me she never had sex without a condom with any customer of hers. She also told me she does not let anyone ejaculate on her body as she is scared of diseases and STD. Now i dont believe any of this as such since at the end she is CSW. I am assuming her to be hiv positive.

After she went I freaked out the next day that I may have caught HIV because of her sucking my nipples if she had any bleeding gums or mouth ulcer. I checked my nipples and did not notice any sign of injury or mark but got very scared and started testing for hiv.I did not notice any blood coming form her mouth and did not have any cut or injury before she sucked my nipples. After the event i checked my nipples repeatedly but could not find any injury or small cut. I am very scared.

please refer to my test results below:-
risk date- april 7,2016
hiv-1 rna QUANTITATIVE pcr on april 18- negative, target not detected (10 days after exposure)
hiv 1/2 & p24 antigen combo test on may 6- index value- 0.07 negative(28 days after exposure)
hiv-2 pcr detection on may 14- negative,target not detected(37 days after exposure)
hiv 1/2 & p24 antigen combo test on may 21- index value- 0.11 target not detected(44 days after exposure)
hiv-1 rna QUALITATIVE PCR on may 24- negative, target not detected(46 days after exposure)

now can i consider myself 100% negative for both hiv-1 and hiv-2 and move on with my life or do i need a confirmation with an antibody testing at 90 day mark? is there a possibility that all my pcr and hiv 1/2 and p24 antigen combo test(CMIA) are false allnegatives? Is the hiv 1/2 & p24 combo test the same as the hiv duo test? I have read that both the duo and pcr test are considered conclusive by 4-6 weeks by hiv specialists... i know u may say that i dont really need testing but please help.

HIV Tests

I had a 5 sexual activity. After 1 year I did HIV PCR test and ELISA antibodies result is negative. Is test reliable? And if ı have a superinfection was it released in test results? Some web sites says cant be detected antibodies. On web a patient with hiv 1 superinfection case. Sorry my bad english

worried

I've had protected sex on 1st May 2016.
1.On the 21th day from exposure, i took the following tests-Hiv antibody/antigen,vdrl,Hepatitis B and C test.All negative.
2.On the 33rd day from exposure ,I've taken HIV 1proviral dna test and 4th generation HIV antibody and P24 antigen test.All negative.Could you please say if the results are conclusive.

P24 antigen + VIH1+2 test

I had a risk behavior so I want to know as much as possible i can.

6-7 Days after the relation, i went to MD and he told me that i have to wait to take hiv test, but in case i couldnt i should take P24 antigen test + VIH1+2 test.

I dont know wich generation the test was, bur the results are:

VIH 1 + 2 NEGATIVE
Technic: Antingen-Antibody reaction

Ag. P 24 NEGATIVE
Technic: WESTERN-BLOT

With this information: is it possible to know wich generation of test the lab performed?
Ag.P 24 is reliable?

I understand that i have to wait to have another test. but with those a made mean something? or do not at all.

Regards

4th gen elisa accuracy after 27 days.

I had protected anal sex (bottom) and unprotected oral sex, I tested 27 days after and the results came back negative. Shld I still be worried or is it almost 100% safe that I am not HIV+?

cut/anilingus

Hi. 24 days ago I received oral and anilingus. I know the risk is negligible for these, but the thing is I had a cut around my anus where he was giving. I don't know why I'm stressing this so much. Is 24 days too soon to get accurate results from a 4th generation test? Also, are you guys related to CDC in terms of information about everything with risks and such?

Unprotected Oral Sex, Elisa Combo and PCR

Hi all
first of all I've to say this helpline is very useful and well done too.
Let's move straighforward to the point. I'm in a homosexual relationship since 3 years but in May we decided both to have one experience each with other guys, always protected insertive sex and both did unprotected oral sex without ejaculation in the mouth and without any sort of contact with blood.
Doing some math
My Boyfriend took an Elisa 4th generation (antibodies + p24) test 35 days after the "possible" exposure with the unprotected oral sex he had, results negative (no reactive).
I took a PCR RNA test after 15 days from the last exposure combined with a Elisa 4th generation test resulting "undetectable , less then 37 copies/ml " and not reactive to the antibody + p24 test.

I know PCR RNA is not a diagnosing tool (but my doctor prescribed me because he found me very anxious) because of high cost, technical problem and high rate of false positive but that actually is a high sensitivity test (so very few false negative results). What I am wondering now is
1) does my boyfriend can take his results as conclusive ?
2) can i take mine as conclusive ?

Now we are 6 (my boyfriend) and 4 (me) weeks after the last possible exposure and we do not have any syntomphs.
Thanks for all !

Is HIV test at 84 days and 85 days conclusive?

Sir,
I did a HIV 1 & 2 and P24 combo (CMIA) test after 84 days of possible HIV infection. I took another test a different lab (HIV 1/2 spot test screening) at 85 days. Both the result came out non-reactive.
Should I go for another test at 90 days or my tests are conclusive?
I recently had a TETANUS VACCINE after my tests. I found on the internet that TETANUS VACCINE can cause false positive in rare cases. I don't want to give myself tension by getting the false positive. Please walk me through all the tests that are not affected by TETANUS VACCINE in detection of HIV 1 &2. I want to relive myself from this HIV (1&2) tension.
In my home city, labs are offering only HIV 1 RNA QUANTITATIVE, REAL TIME PCR. Will it work? What about HIV 2?
Please help

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