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2 pos Elisa, Neg WB, help

Question: 

Hello, thanks for helping me with my doubtful situation.
I´m an homosexual 25 y/o male.
Past march 25th, 2016 I tested positive with a 4th generation ELISA test. I repeated the test in a State hospital wich came back again Positive (value=21). Next, they performed the confirmatory Western Blot wich came back negative with no bands. At the same time of tests i had an acute streptococcal pharingytis in course wich resolved hardly with antibiotic treatment.

I've been sexually active since 2015 but i've prcaticed safe sex. I've had receptive penetrative acts (2 or 3) all protected and unprotected oral sex with no in-mouth ejaculation or similar. I dont see any potential risk, am I wrong? I also had not any seroconversion-like illness and a recent CD-4 test gave a 534 number.

My doctor keeps on telling me that i have to retest because he thinks my WB is a false negative. But HIV specialist says It's not necessary. My question: Do I really have to re-test since my low risk? Is a false negative WB possible?
Many thanks.

Answer: 

Hello and thanks for contacting AIDS Vancouver with your question. It sounds like you are concerned about the reliability of your test results, and the conflicting information from your doctors about whether or not to be retested.

You are correct in saying that the activities that you have described (penetrative sex with a condom/giving oral sex) are considered Low Risk. This means that, the practices assigned to this risk level present a potential for HIV transmission because they involve an exchange of body fluids. There have been a few reports of infection attributed to these activities (usually under certain identifiable conditions).

The concern seems to be surrounding the negative Western Blot test result, and whether or not you should retest. The Western Blot test detects HIV antibodies directed against specific HIV proteins. The window period for this test is 4-6 weeks, and may take up to 8 weeks for a positive result. It is standard test protocol as confirmatory test. The Western Blot is considered to be "gold standard" for confirmation of HIV infection. Accuracy is 99.9% after 4-6 weeks

Here at AIDS Vancouver we recommend that everyone make HIV testing a part of their regular healthcare maintenance routine. It's great that you've made your commitment to testing! I cannot tell you the likely hood of whether or not there is a chance in your situation that Western Blot was a false negative. What I can tell you is that decision whether or not to retest is up to you. Even if after reading the information provided you still want more peace of mind, a retest may help to put your mind at ease.

I would encourage you to check out the following resources for more information about HIV:

Thanks for contacting AIDS Vancouver.

Hilary

AIDS Vancouver Online Helpline
helpline.aidsvancouver.org
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