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i had 4th gen test negative after one month however I have ezcema and taken hydrocortisone wold that have affected the test as well as i have polycystic ovarian syndrome?


Hello and thanks for contacting AIDS Vancouver with your question.

It sounds like you have some concerns about your HIV test results.

From what you have told me, you pursued a 4th generation test one month post-exposure and it produced a negative result, but are concerned as you are currently dealing with eczema, taking hydro-cortisone and you have poly-cystic ovarian syndrome. First off, it is great that you went out and pursued HIV testing. It takes a lot of courage to pursue HIV testing and it is great to stay up to date on your current HIV status. The 4th generation test is a blood test that looks for antibodies and P24 protein antigens. Furthermore, the P24 is detectable immediately after infection and only for the first few weeks. The antibody test has a window period of 4-12 weeks. Most HIV specialists consider this "DUO" test conclusive at 6 weeks. However, when it comes to this test official HIV testing guidelines still recommend re-testing at 12 weeks for completely conclusive results.

There are only 4 situations where your HIV test window period may be affected. They are:

1) Antiviral treatment for Hepatitis C

2) Treatment for Cancer (Chemotherapy)

3) P.E.P treatment for HIV

4) Other immunodeficiency diseases

From what you have told me, you currently do not have any of the above and your window period will still be normal. Even with the factor of poly-cystic ovarian syndrome, it is a hormonal disorder and not any of the above.

For more information on HIV testing you can visit AVERT HIV Testing.


Chris, Volunteer

AIDS Vancouver Online Helpline
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