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HIV

Question: 

On may 29 2016 i had a one time protected vaginal sex with prostiture(female) in india(hyderabad).
1. On 19th day i had a pcr rna test,result was negative.
2. on 32 day i had p24 antigen test for HIV(1&2) and after next day i had hiv1&2 antibody test,reuslt was negative.
3. On 46 day i had HIV1&2 Elisa test the reulst was negaive.
Now i am confident that,hiv-1 can be eliminated by above test reports
Now i am worrying about hiv-2,is there any chance still hiv-2 hidden in my body.

Answer: 

Hi there, and thanks a lot for contacting the AIDS Vancouver Helpline for your HIV/AIDS related health information. It seems you have some questions about the accuracy of some tests you've had after an encounter. We're happy to answer your questions for you.

First off, consider that protected sex is considered a low risk activity. Low risk means that while transmissions are possible, they require specific circumstances to occur (like the condom breaking, for example). To see the risks associated with many common activities, we encourage you to check out our risk assessment page.

Here is a bit more information on the tests you've had:

Test Name
Method
Window Period
Conditions
Pooled RNA NAAT or “Early Test” Detects viral RNA in blood of people who have yet to develop detectable antibody levels. 10-12 days post exposure The pooled RNA test is often expensive and not readily available. One must be referred by a health care professional to receive this test. An antibody follow up test after 12 weeks is sometimes necessary depending on how long after the exposure the test was performed. Conclusive at 3 months post exposure.
4th Generation EIA Blood test that looks for antibodies AND p24 protein antigens. Commonly referred to as the "combination," "combo" or "DUO" test. P24 protein is detectable immediately after infection but only for the first few weeks. The antibody (ab) test has a window period of 4-12 weeks post exposure. This test is widely available in North America. Most HIV specialists consider this test to be conclusive at 6 weeks but official HIV testing guidelines still recommend re-testing at 12 weeks for conclusive results. Conclusive at 3 months post exposure.
EIA (Enzyme Immunoassay) antibody 3rd Generation aka ELISA Blood test that looks for antibodies 4 weeks to 3 months (although up to 95% of infections are detectable within 4-6 weeks). Most people develop detectable antibodies in 21-25 days. Most commonly available testing method. We are encouraged to hear that 4th gen tests are on their way to Vancouver but currently are only available via referral. Conclusive at 3 months post exposure

You'll see in the chart that all of the tests you've had completed are considered conclusive, meaning the results are taken as accurate, 3 months or 90 days post exposure. You've had tests on day 19, 32 and 46 post exposure, which are actually too soon to show your status conclusively. As for your question about HIV-2 somehow remaining hidden in your body, know that these tests are for all types of the virus. It is not possible that you be infected and for it to not show up on these tests provided they are not done in the window period.

Thanks a lot for contacting the AIDS Vancouver Helpline with your questions, we hope they've been answered fully.

Trevor

AIDS Vancouver Helpline/Online
helpline.aidsvancouver.org