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HIV duo combo CMIA test


If HIV duo combo test CMIA is negative after 100 days of exposure, is there anything to worry?



Thank you for your inquiry. From what we gather from the question, you were asking about the accuracy of a negative result from the 4th Generation Duo test, 100 days post exposure.

Fourth-generation HIV tests can detect HIV infection in 50% of people by 18 days after infection; 95% of people by 34 days after infection; and 99% of people by one and a half months after infection(1). Most HIV specialists consider this "DUO" test conclusive at 6 weeks. However, official HIV testing guidelines still recommend re-testing at 12 weeks for completely conclusive results, when accuracy is 99.9%.

The negative result received 100 days post exposure was received after the 12 weeks, when official HIV testing guidelines consider this test completely conclusive. This means that the negative result received is considered completely conclusive and has an accuracy of 99.9%.

Recommendation: Test result considered conclusive at 12 weeks. No further testing is required. Refer to your healthcare professional for any other health related concerns.

Regards, AIDS Vancouver Helpline/Online, Hilary