I had an exposure 115 days (16.5 weeks) ago ( protected sex at a massage parlor, un covered blow job and pussy licking). NO PEP
I had a HIV 4th gen and HIV RNA test ( both at Loabcorp and Quest) on week 6, 12 and 15. All were Non reactive(for 4th gen) and NON detectable(for RNA). Can I 100% consider conclusive HIV negative with my week 15 test( 105 days after exposure). I read some threads about 2nd hiv window period and late seroconverstion in some people. Would those people also be conclusive by week-15. Also on some websites it still says they recommend another test on 6month mark, is completely outdated info.
is there any possibility or scenario for antibodies and antigens to stay at a very low un detectable level for the 4th gen and RNA tests on week-15
I wanted to make sure that am 100% safe with my 3 neagtive results and can safely move on with my normal life and sexual activities.
Thank you for your inquiry. From what we gather from the question, you were asking about the risk of having HIV after protected sex and receiving negative results from a 4th generation EIA (Enzyme Immunoassay). From the information given, this scenario is determined to be No Risk (HIV transmission is not possible in the given scenario).
Fourth-generation tests are extremely sensitive and specific. The threads you have read are probably inaccurate as evidence-based studies show that re-testing at 12 weeks is considered to have completely conclusive results (accuracy is 99.9%)(1).
Recommendation: No need for HIV test with the scenario provided, refer to a healthcare professional for other health related questions.
Regards, AIDS Vancouver Helpline/Online, Samantha