Piyu_m
Please help very scared !
 
I'm from India and after a condom slippage incident and had uprotected oral sex 4 months ago, I have taken four duo tests by ( ELFA method) antigen plus antibody tests at 4,8,12 and 15 weeks all at the same lab and all negative. The lab is one of the most reputed labs here and they are professional. 
 
1. Please tell me if I can consider the tests conclusive or should I change my test to a 3rd generation test or a 4th generation test by (CMIA method ) at a different lab?
 
2. Is the 4th generartion test by CMIA and ELFA method one and the same?
 
3. Will a change in test or lab will give me a different result? I have heard sometimes changing the lab or the test gives a different result. Is it true?
 
 Am  I HIV negative conclusively?
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helpline-volunteer

Hello,


Thank you for your inquiry. From what we gather from the question, you were asking about the accuracy of the HIV tests you have accessed after engaging in protected insertive sex. From the information given, this scenario is determined to be Low Risk (evidence of transmission occurs through these activities when certain conditions are met).

The scenario mentioned above could meet the three components of the transmission equation. Since condoms are not 100% effective at preventing transmission of sexually transmitted infections, and you mentioned that slippage may have occurred, there is a risk that bodily fluids containing the HIV virus had direct access to your bloodstream.
Helpline Transmission Equation .jpg
It was very responsible of you to access testing after engaging in risky behaviour. The 4th generation ELFA "duo" tests you have accessed are considered conclusive by most HIV specialists 6 weeks post-exposure, and completely conclusive by other physicians and some guidelines 3 months post-exposure. A 4th generation test can detect both the HIV virus itself as well as antibodies that your body would produce if you were exposed to and acquired HIV. This is in contrast to a 3rd generation test that only detects the presence of antibodies. Thus, switching to a 3rd generation test would not be beneficial, as it is considered to be slightly less good at detecting active HIV infections, and switching to another 4th generation test would not provide a different outcome.

Recommendation: Since you have accessed testing outside of the window period, no further testing is required. Refer to a healthcare professional for more personalized answers.

Regards,

AIDS Vancouver Helpline/Online, Marie
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