I had unprotected sex 17 weeks ago. I had 4 HIV tests at 6,9,12 and 16 weeks. They all came back negative.
Now i still have some issues that i didn't have before my exposure. I feel soms small bumps at the back of my nek and one big bump at the front next to my esophagus at the muscle that goes from shoulder to shin. I thought it was a swollen lymphe node, my doctor thought it also but when my results of the bloodtest came back he said that it isn't a lymphe node because my blood doesn't show an infection and the hiv test is negative.
He thought it was a muscle node. But i read that a muscle node is hard and can't move. but this bump is a little bit hard and very movable.
So now i keep thinking that it is a lymph node and that my body doesn't have made any antibodies against the virus. That HIV is in my body but that the test doesn't show it. The 4 HIV tests are 4th generations tests i think. Because on my bloodtest stood ( HIV 1&2 ( Ag/ab)).
Do you think that i am one of the persons that hasn't developed any antibodies yet, but that i need to re-test 6 month periode to be shure that it isn't HIV?

Thanks for answering my question!

Thank you for your inquiry. From what we gather from the question, you were asking about the accuracy of your 4th Generation Duo tests and whether or not you should retest at 6 months. You state that you took these tests an unprotected sexual encounter, which is considered to be a High Risk activity (evidence of transmission through these activities and is the majority of cases of transmission).

The 4th Generation Duo test is a blood test that looks for antibodies AND P24 protein antigens. It is commonly referred to as the "combination," "Combo" or "DUO" test. Fourth-generation HIV tests can detect HIV infection in 50% of people by 18 days after infection; 95% of people by 34 days after infection; and 99% of people by one and a half months after infection(1).

Most HIV specialists consider this "DUO" test conclusive at 6 weeks. However, official HIV testing guidelines still recommend re-testing at 12 weeks for completely conclusive results, when accuracy is 99.9%.

You state that you have had four 4th Generation Duo tests. These tests were taken 6 weeks, 9 weeks, 12 weeks and 16 weeks post exposure. They all came back negative. The first test was administered at 6 weeks, when most HIV specialists consider this "DUO" test conclusive. The other 3 tests were administered at the 12 week mark or after the 12 week mark, when official HIV testing guidelines consider the results of this test to be completely conclusive, with an accuracy of 99.9% (1).

This means that your negative results are completely conclusive, and there is no need for a further test.

We cannot say that the symptoms you are experiencing are due to HIV infection. These symptoms can be attributed many other viral infections. We encourage you to visit your healthcare professional to discuss any symptoms you many be having.

Recommendation: HIV testing resulted considered conclusive. No need for another HIV test with the scenario provided. Refer to your healthcare professional for any symptoms or other health related questions.

Regards, AIDS Vancouver Helpline/Online, Hilary
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