Anonymous
Exposure - unprotected vag. Combo test and pcr rna test at 10 and 24 days - negative. Extremely high anxiety.
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Anonymous
Hello and thanking for using AIDS Vancouver as your source for HIV/AIDS related information.

In order for HIV transmission to occur, body fluids with high levels of HIV such as blood, semen/pre-cum, and anal/vaginal fluids must have direct access into the blood stream of someone who is HIV negative. Examples of areas that have direct access to the blood stream are the vagina/penis urethra, anus, other mucosal membranes, and points of needle injection. Unprotected vaginal sex is considered a high risk activity.

I'm going to provide you with some general information about the HIV tests you took.

The PCR RNA test examines the level of viral RNA in the blood, it is presently only available for men. The window period for testing is 2-3 weeks post potential exposure with results that are 90% accurate at 10-12 days; 95-98% accurate at 6 weeks; and conclusive after 12 weeks (3 months). Although results taken at these time frames are considered accurate, they are not considered conclusive, as according to the World Health Organization, unless they (any HIV test) are taken at 3 months post potential exposure.

The combo test is a 4th generation test that examines two markers in the blood sample to provide very accurate results. The first marker examined are the levels of antibodies in the blood. Antibodies are developed in the blood as a response to HIV infection, they are usually detectable from 3-4 weeks onwards of exposure to HIV. The second portion of the test will check P24 antigen levels in the blood. This antigen is detectable immediately after exposure to HIV; this antigen is what produces the antibody response to HIV.By testing both of these markers, this test is considered to be one of the most accurate tests available by many health care specialists at 6 weeks; as previously mentioned however, the World Health Organization considers all tests conclusive at 3 months post potential exposure.

In regards to your question about the dates of your HIV tests, neither of the tests on those dates would provide conclusive results. In order to obtain conclusive results, you would have to take another test at 3 months post potential exposure. However, if you did take the combo test at 6 weeks post potential exposure it may provide you with some anxiety relief before re-testing at 3 months to receive conclusive results. The combo test results at 6 weeks are unlikely to change with the re-test at 3 months as they do provide accurate results.

We hope to have answered your question. For more information on testing or transmission you can look at our online forum at [AIDS Vancouver](http://www.aidsvancouver.org)

In health,

Johannah
AIDS Vancouver Helpline Volunteer

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