if symptoms of acute phase appears in the sixth week after exposure risk and be performs a fourth generation test in the seventh week and a third-generation in the eighth week. can they come non reactive? I read that after the acute phase, the testing return non reactive.

which opinion about it!

thank you!
Hello and thanks for reaching out to the AIDS Vancouver Helpline.

It seems like you want to gather information regarding the two HIV test that you done after exposure.

Antibody tests (such as the 3rd Generation) are reliable from 4 weeks post exposure, whilst combination (antigen and antibody, such as the 4th Generation) test are reliable earlier. Both of these tests are considered conclusive at 12 weeks post-exposure, however a result from 7 weeks would be a really great indicator of your HIV status. For these tests, a "non-reactive" result would indicate a "negative" status.

Here is the link that will give you more information regarding the third and fourth generations that we do in Canada.

EIA 3rd Generation

4th Generation EIA
Test Name Method Window Period Conditions
Enzyme Immunoassay Antibody (EIA) 3rd Generation (ELISA) Blood test that looks for antibodies. Up to 95% of infections are detectable within 4-6 weeks post exposure. Most people develop detectable antibodies in 21-25 days. Most commonly available testing method. Conclusive at 3 months post exposure.

I hope this information is helpful and you might want to explore this websites: [AIDS Vancouver ][] and [CATIE ][].

Thank you for contacting the AIDS Vancouver Helpline.

Best in Health!


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Test Name Method Window Period Conditions
4th Generation EIA Blood test that looks for antibodies AND p24 protein antigens. Commonly referred to as the "combination," "combo" or "DUO" test. P24 protein is detectable immediately after infection but only for the first few weeks. The antibody test has a window period of 4-12 weeks post exposure. This test is widely available in North America. Most HIV specialists consider this test to be conclusive at 6 weeks but official HIV testing guidelines still recommend re-testing at 12 weeks for conclusive results. Conclusive at 3 months post exposure.