Hello, doctor, I really have no way out, my body is killing me, I ask for your help.

My English is not good, thank you for you patient to see follow content.

I. behavior: four months ago, I had unprotected sex with a sex worker (later, she tested positive for HIV antibody, which she did not know at that time). I took the blocking drug (PEP)73 hours after the occurrence of high-risk behavior.

2. Testing: after taking the drug (one month at high risk), the test was negative for antigens and antibodies; four months at high risk (three months after stopping the drug) was negative for antigens and antibodies; nucleic acid and RNA were not detected.

3.Physical condition:

During taking the blockerPEP: retching every morning + eating nausea

After stopping the blocking drug (PEP):

1. Never long rashes, stop blockers didn't take long to have the rash lasts for three months, always itch and peel, I was treated at several hospitals , with compound polymyxin ointment didn't work for a month and then wipe, west to acid + oral erythromycin enteric capsules for a month, the rash is still not better, had no choice but to go to the hospital of dermatology, the doctor checked with blade, skin infections, they consider it like AIDS, syphilis rash, do let me check, but my syphilis all right in a hospital which has the hiv expert have checked twice.

2. Headaches, sore throats, loose bowels, fatigue, aches and pains all over the body. I went to four or five hospitals for check. After taking the medicine for more than three months now, my condition is still the same. Every time have loose bowels is pull of water and it occurs for 3 or 4 times a day. My head hurts for a long time and I can't carry it. But I am too painful, the body will wake up automatically in the middle of the night every day 4 or 5 times, the body pain, daytime fatigue, muscle acid pain, can only rely on continuous sleep to alleviate, specific is the body state after the vaccine, really not my pressure caused by the fatigue. Now I have to sleep every day and night, because my headache is so severe that I can only sleep to relieve it. Otherwise, I have to take painkillers. If I don't sleep, I will be very tired and my body will enter a state of unconsciousness.

4. Doubt

Other doctors all say can be ruled out for three months, I also very, very want to rule out, but my body told me that the situation is very serious, I quit early work, stay home, thought accomplishment for a period of time the body can be good, but as the stop blocking drug time longer and longer, are more serious illness, sometimes too painful, basic life issues, there will be a suicide ideas (not psychological pressure, personal situation known to family, family only want my body to restore). Trouble you to help me analysis analysis, see how do I, if still can't confirmed, I will buy medicine to eat, so every day carrying a sickness, health is becoming worse, every day I feel in my body condition so it can only live again two or three years, I was eating during the blocking just dry heaves and nausea, no other so many condition, because of the suffering of every moment in my expression may be some drama in your eyes, but his condition I really is to be honest, very thank you very much.



Thank you for your inquiry. From what we gather from the question, you were asking about the symptoms you have been experiencing after engaging in unprotected insertive sex. From the information given, this scenario is determined to be High Risk (there is evidence of transmission through these activities and are the majority of cases of transmission).

The scenario mentioned above
does meet the three components of the transmission equation.
Helpline Transmission Equation .jpgAccessing PEP after engaging in a risky activity is a great way to reduced the chance of an HIV transmission occurring. Unfortunately, the effectiveness of a PEP prescription that is started more than 72 hours post-exposure is greatly reduced (1). It is important to note that the sooner PEP is started, the more likely it is that it will effectively prevent an HIV transmission.

In regards to the testing you accessed, all 3rd and 4th generation tests are considered completely conclusive 3 months post-exposure (2,3). If PEP is accessed, then the window period resets and the tests will be considered completely conclusive 3 months post-PEP completion. Since you received a negative HIV test result outside of the window period, it is unlikely that you acquired HIV from this exposure.

The symptoms you noted are very troubling. When taking PEP medication, experiencing nausea, tiredness, and generally feeling unwell are all common occurrences. Post-PEP, it is very unlikely that the symptoms you are continuing to experience are due to an HIV infection. I understand that experiencing symptoms that make it near impossible to live your daily life is frustrating. Please continue to reach out to the healthcare providers in your area to address all of your concerns, both physical and mental.

Recommendation: No further testing is required since testing has been accessed outside of the window period. Refer to a healthcare professional for more personalized answers.

AIDS Vancouver Helpline/Online, Marie

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